منابع مشابه
A Comparative Study on Three Analytical Methods for the Determination of the Neurotoxin BMAA in Cyanobacteria
The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) has been considered a serious health threat because of its putative role in multiple neurodegenerative diseases. First reports on BMAA concentrations in cyanobacteria were alarming: nearly all cyanobacteria were assumed to contain high BMAA concentrations, implying ubiquitous exposure. Recent studies however question this presence o...
متن کاملThe Emerging Science of BMAA: Do Cyanobacteria Contribute to Neurodegenerative Disease?
Books 2005–2009 [website]. Northampton, United Kingdom:Motor Neurone Disease Association. Available: http://www.mndassociation.org/research/for_researchers/ international_symposium/previous.html [accessed 3 Feb 2012]. 46. Rao SD, et al. BMAA selectively injures motor neurons via AMPA/ kainate receptor activation. Exp Neurol 201(1):244–252 (2006); http://dx.doi.org/10.1016/j.expneurol.2006.04.01...
متن کاملEditorial: Cyanobacteria: The Green E. coli
As the world struggles to reduce its dependence on fossil fuels and curb greenhouse gas emissions, industrial biotechnology is also " going green. " Escherichia coli has long been used as a model Gram-negative bacterium, not only for fundamental research but also for industrial applications. Recently, however, cyanobacteria have emerged as candidate chassis for the production of commodity fuels...
متن کاملDetection, transfer and role of an environmentally spread neurotoxin (BMAA) with focus on cyanobacteria and the Baltic Sea region
β-N-methylamino-L-alanine (BMAA) is one of the more recently discovered bioactive compounds produced by cyanobacteria. BMAA is a non-protein amino acid reported present in human brain tissues of patients deceased from a neurodegenerative disease, such as Alzheimer ́s disease or amyotrophic lateral sclerosis (ALS). This observation in combination with its neurotoxic effects in eukaryotes (in vivo...
متن کاملProduction of the Neurotoxin BMAA by a Marine Cyanobacterium
Diverse species of cyanobacteria have recently been discovered to produce the neurotoxic non-protein amino acid beta-methylamino-L-alanine (BMAA). In Guam, BMAA has been studied as a possible environmental toxin in the diets of indigenous Chamorro people known to have high levels of Amyotrophic Lateral Sclerosis/ Parkinsonism Dementia Complex (ALS/PDC). BMAA has been found to accumulate in brai...
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ژورنال
عنوان ژورنال: Revista Neurociências
سال: 2019
ISSN: 1984-4905,0104-3579
DOI: 10.34024/rnc.2009.v17.8589